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63478-76-2

  • Product Name6-Heptyn-1-ol
  • Molecular FormulaC7H12O
  • Molecular Weight112.172
  • Purity99%
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Product Details

Quick Details

  • CasNo: 63478-76-2
  • Molecular Formula: C7H12O
  • Purity: 99%

Trustworthy Factory Supply Top Purity 99% 6-Heptyn-1-ol 63478-76-2 with the Best Price

  • Molecular Formula:C7H12O
  • Molecular Weight:112.172
  • Vapor Pressure:0.378mmHg at 25°C 
  • Melting Point:-20.62°C (estimate) 
  • Refractive Index:1.452 
  • Boiling Point:174.3 °C at 760 mmHg 
  • PKA:15.14±0.10(Predicted) 
  • Flash Point:92.8 °C 
  • PSA:20.23000 
  • Density:0.894 g/cm3 
  • LogP:1.17230 

6-Heptyn-1-ol(Cas 63478-76-2) Usage

Chemical Properties

6-Heptyn-1-ol is Pale Yellow Oil

Uses

6-Heptyn-1-ol reagents used in the preparation of many cyclic compounds.

Synthesis Reference(s)

The Journal of Organic Chemistry, 49, p. 5175, 1984 DOI: 10.1021/jo00200a032

InChI:InChI=1/C7H12O/c1-2-3-4-5-6-7-8/h1,8H,3-7H2

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The combination of ring-closing metathes...

Total synthesis of two novel brominated acetylenic diols (+)-diplyne C and E: Stereoselective construction of the (E)-1-bromo-1-alkene

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The total syntheses of the enantiomers o...

On the intramolecular pyrone Diels-Alder approach to basiliolide B

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A unified synthetic approach to the basi...

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In this paper we present a study into th...

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Total Synthesis of a Mycolic Acid from Mycobacterium tuberculosis

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The first total synthesis of the tetrasu...

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63478-76-2 Process route

3-heptyn-1-ol
14916-79-1

3-heptyn-1-ol

1-hydroxy-6-heptyne
63478-76-2

1-hydroxy-6-heptyne

Conditions
Conditions Yield
With sodium hydride; Trimethylenediamine; at 20 ℃; for 0.666667h;
100%
With potassium tert-butylate; sodium hydride; Trimethylenediamine; In mineral oil; at 20 - 70 ℃; for 3h;
99%
With potassium tert-butylate; lithium; Trimethylenediamine; at 20 ℃; for 2h;
97%
With potassium hydride; Trimethylenediamine; at 20 ℃; Inert atmosphere;
97%
With sodium hydride; ethylenediamine; In mineral oil; at 10 ℃;
93%
With sodium amide; Trimethylenediamine; In various solvent(s); at 80 ℃; for 2h;
90%
With sodium hydride; ethylenediamine; In various solvent(s); at 65 ℃; for 1h;
83%
With sodium hydride; ethylenediamine; at 65 ℃; for 1h;
83%
With sodium hydride; Trimethylenediamine; at 70 ℃; for 1.5h;
83%
With sodium hydride; In ethylene-1,2-diamine; Inert atmosphere;
81%
With potassium tert-butylate; lithium; Trimethylenediamine;
80%
With potassium salt of 1,3-diaminopropane; for 1.5h; Ambient temperature; sonicated;
78%
3-heptyn-1-ol; With sodium hydride; ethylenediamine; at 45 - 60 ℃; for 1h; Inert atmosphere;
With hydrogenchloride; In water; ethylenediamine; at 0 ℃; Inert atmosphere;
78%
With sodium hydride; In ethylenediamine; at 0 - 60 ℃;
72%
With sodium amide; Trimethylenediamine; at 80 ℃; for 2h;
71%
With sodium hydride; ethylenediamine; at 60 ℃;
68%
With sodium hydride; ethylenediamine; In mineral oil; at 45 - 60 ℃; Inert atmosphere;
68%
With sodium hydride; ethylenediamine; Inert atmosphere;
64%
3-heptyn-1-ol; With sodium hydride; ethylenediamine; at 20 - 65 ℃; Inert atmosphere;
With hydrogenchloride; In water; for 4h; Inert atmosphere;
60%
With lithium; In Trimethylenediamine; at 40 - 60 ℃; Inert atmosphere;
48%
With lithium; Trimethylenediamine; at 40 - 60 ℃;
48%
With sodium hydride; Trimethylenediamine; In mineral oil; pentane; at 0 - 70 ℃; for 1.5h;
21%
With potassium salt of 1,3-diaminopropane; Trimethylenediamine;
 
With potassium salt of 1,3-diaminopropane; ammonium chloride; Yield given. Multistep reaction; 1.)1,3-diaminopropane, 4 h, R.T., 2.)ether, 0 deg C;
 
With sodium hydride; at 20 - 70 ℃; for 2h; Inert atmosphere;
 
hep-2-yn-1-ol
1002-36-4

hep-2-yn-1-ol

1-hydroxy-6-heptyne
63478-76-2

1-hydroxy-6-heptyne

Conditions
Conditions Yield
With potassium hydride; 1,2-diaminopropan; In tetrahydrofuran; mineral oil; at 20 ℃; for 24h; Inert atmosphere;
99%
With potassium salt of 1,3-diaminopropane; In tetrahydrofuran; at 0 ℃; for 0.5h;
97%
With potassium tert-butylate; lithium; Trimethylenediamine; at 20 ℃; for 3h; Inert atmosphere;
90%
With potassium salt of 1,3-diaminopropane;
88%
With sodium hydride; ethylenediamine; at 60 ℃;
88%
With potassium salt of 1,3-diaminopropane;
87%
With potassium tert-butylate; lithium; ethylenediamine; for 3h;
83%
With lithium 2-aminoethylamide; In ethylenediamine; for 0.333333h; amide-hydrocarbon ratio 7:1;
82%
With potassium hydride; Trimethylenediamine; for 2h; cooling;
79%
hep-2-yn-1-ol; With potassium tert-butylate; lithium; Trimethylenediamine; at 20 ℃; for 1h;
With water;
74%
With potassium salt of 1,3-diaminopropane; Trimethylenediamine;
73%
With potassium hydride; ethylenediamine; at 20 ℃;
70%
With potassium hydride; In various solvent(s); at 10 - 15 ℃; for 1.5h;
67%
With sodium hydride; ethylenediamine; at 60 - 65 ℃; for 3h;
64%
With sodium hydride; ethylenediamine; In mineral oil; at 0 - 70 ℃;
61%
With potassium hydride; Trimethylenediamine;
46%
With potassium salt of 1,3-diaminopropane; at 20 ℃; for 1h;
1.09 g

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