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2466-76-4

  • Product Name1-Acetylimidazole
  • Molecular FormulaC5H6N2O
  • Molecular Weight110.115
  • Purity99%
  • Appearancewhite to beige or light tan adhering crystals
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Product Details

Quick Details

  • CasNo： 2466-76-4
  • Molecular Formula： C5H6N2O
  • Appearance： white to beige or light tan adhering crystals
  • Purity： 99%

Reputable Factory Supply High Purity 1-Acetylimidazole 2466-76-4 with Fast Shipping

  • Molecular Formula:C5H6N2O
  • Molecular Weight:110.115
  • Appearance/Colour:white to beige or light tan adhering crystals 
  • Vapor Pressure:0.104mmHg at 25°C 
  • Melting Point:99-105 °C(lit.) 
  • Refractive Index:1.552 
  • Boiling Point:221.955 °C at 760 mmHg 
  • PKA:pKa 3.6(H2O,t = 25,I=0.2) (Uncertain) 
  • Flash Point:88.035 °C 
  • PSA：34.89000 
  • Density:1.146 g/cm3 
  • LogP:0.54320 

1-Acetylimidazole(Cas 2466-76-4) Usage

Chemical Properties

white to beige or light tan adhering crystals or

Uses

Acetylating agent for capping unreacted amino groups in peptide synthesis.

General Description

Rate of solvolysis of 1-acetylimidazole in acid solutions was evaluated. Reaction of 1-acetylimidazole with orthophosphate and adenosine-5′-phosphate has been reported.

Purification Methods

It is recrystallised from isopropenyl acetate and dried in a vacuum over P2O5. [Riordan & Valee Methods Enzymol 25 500 1972, Beilstein 23/4 V 218.]

InChI:InChI=1/C5H6N2O/c1-5(8)7-3-2-6-4-7/h2-4H,1H3

2466-76-4 Relevant articles

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Brinigar,Knaff

, p. 406 (1965)

-

-

Gelas,Horton

, p. 323,324, 325 (1978)

-

Silica Subsurface Amine Effect on the Chemical Stability and Chromatographic Properties of End-Capped Immobilized Artificial Membrane Surfaces

Invergo, Ben,Alvarez, Francisco M.

, p. 1851 - 1860 (1991)

The silica surface of immobilized artifi...

Differentiation of Nucleophilic and General Base Catalysis in the Hydrolysis of N-Acetylbenzotriazole Using the Proton Inventory Technique

Gopalakrishnan, Ganesa,Hogg, John L.

, p. 4959 - 4964 (1981)

The hydrolysis of N-acetylbenzotriazole ...

Synthesis, characterization and spectroscopic studies of two new 1-acetyl-3-alkylimidazolium ionic liquids

Huanhuan, Xu,Wenjuan, Zhu,Pingmei, Wang,Dafei, Wang,Qiang, Li

, p. 179 - 181 (2013)

Two new functionalized ionic liquids, 1-...

-

Wenck,H.,Schallies,M.

, p. 3059 - 3071 (1973)

-

DNA AFFINITY CLEAVING SEQUENCE SPECIFIC CLEAVAGE OF DNA BY DISTAMYCIN-EDTA*Fe(II) AND EDTA-DISTAMYCIN*Fe(II)

Taylor, John S.,Schultz, Peter G.,Dervan, Peter B.

, p. 457 - 465 (1984)

The attachment of EDTA*Fe(II) to distamy...

Complementary PCAF-Coenzyme a mutagenesis: Chemoenzymatic synthesis of a novel enlarged coenzyme a analogue and evaluation of its biological activity

Khim, Leang,Han, Juan,Willetts, Lynsey,Brady, Kevin,Gillece, Pauline,Rached, Ouannassa,Thomas, Neil R.,Stylianou, Eleni

, p. 2100 - 2103 (2010)

-

An efficient catalytic method for the c-n acylation of heterocycles by schiff base co(Ii), ni(ii), cu(ii) and zn(ii) transition metal complexes

Hegade, Sujit,Gaikwad, Gautam,Jadhav, Yuvraj,Chavan, Sanjay,Mulik, Ganpatrao

, p. 611 - 616 (2021/09/30)

The catalytic activity of Schiff base Co...

Facile one-pot synthetic access to libraries of diversely substituted 3-aryl (Alkyl)-coumarins using ionic liquid (IL) or conventional base/solvent, and an IL-mediated approach to novel coumarin-bearing diaryl-ethynes

Kalkhambkar, Rajesh G.,Laali, Kenneth K.,Malunavar, Shruti S.,Prabhala, Pavankumar,Savanur, Hemantkumar M.,Sutar, Suraj M.

supporting information, (2020/04/08)

The in-situ formed carbonylimidazole der...

Length-Selective Synthesis of Acylglycerol-Phosphates through Energy-Dissipative Cycling

Bonfio, Claudia,Caumes, Cécile,Duffy, Colm D.,Patel, Bhavesh H.,Percivalle, Claudia,Tsanakopoulou, Maria,Sutherland, John D.

supporting information, p. 3934 - 3939 (2019/03/08)

The main aim of origins of life research...

Efficient CDI/CH3SO3H-catalyzed, microwave-assisted synthesis of 2-substituted benzothiazoles

Li, Yao-Wei,Zhang, Pei-Ming,Li, Rui,Bai, Yan,Yu, Yu,Gan, Zong-Jie

supporting information, p. 34 - 39 (2019/05/04)

CDI combined with CH3SO3H was found to b...

2466-76-4 Process route

1H-imidazole
288-32-4

1H-imidazole

4-nitrophenol acetate
830-03-5

4-nitrophenol acetate

N-Acetylimidazole
2466-76-4

N-Acetylimidazole

4-nitro-phenol
100-02-7,78813-13-5,89830-32-0

4-nitro-phenol

Conditions
Conditions Yield
With dm-3 borate buffer; at 25 ℃; Rate constant; pH 9.00; also in the presence of cyclodextrins at var conc.;
 
With sodium dodecyl-sulfate; In water; acetonitrile; at 25 ℃; pH=8.92; Further Variations:; Reagents; Kinetics;
 
In ethanol; water; Temperature; Activation energy; Kinetics; Mechanism;
 
1H-imidazole
288-32-4

1H-imidazole

2,3-dichlorophenyl acetate
61925-85-7

2,3-dichlorophenyl acetate

N-Acetylimidazole
2466-76-4

N-Acetylimidazole

2,3-dichlorophenol
576-24-9

2,3-dichlorophenol

Conditions
Conditions Yield
With sodium dodecyl-sulfate; In water; acetonitrile; at 25 ℃; pH=8.92; Kinetics;
 

2466-76-4 Upstream products

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;

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