What is the Eicosanedioic acid?

Eicosanedioic acid is , while it's Molecular Formula is C20H38 O4. Eicosanedioic Acid is an intermediate used to prepare haloperidol-based bivalent ligands targeting dopamine D2-like receptors.

What is the CAS number for Eicosanedioic acid?

The CAS number of Eicosanedioic acid is 2424-92-2.

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Product Details

Quick Details

CasNo： 2424-92-2
Molecular Formula： C20H38 O4
Purity： 99%

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Molecular Formula:C20H38 O4
Molecular Weight:342.519
Vapor Pressure:1.57E-11mmHg at 25°C
Melting Point:127°C
Refractive Index:1.4430 (estimate)
Boiling Point:504.1°Cat760mmHg
PKA:4.48±0.10(Predicted)
Flash Point:272.8°C
PSA：74.60000
Density:0.984g/cm³
LogP:6.17740

Eicosanedioic acid(Cas 2424-92-2) Usage

Uses	Eicosanedioic Acid is an intermediate used to prepare haloperidol-based bivalent ligands targeting dopamine D2-like receptors.
Definition	ChEBI: An alpha,omega-dicarboxylic acid that is the 1,18-dicarboxy derivative of octadecane.

InChI:InChI=1/C20H38O4/c21-19(22)17-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-18-20(23)24/h1-18H2,(H,21,22)(H,23,24)/p-2

2424-92-2 Relevant articles

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Guenthard et al.

, p. 1147,1158 (1953)

Preparation method of long-chain aliphatic dicarboxylic acid mono-tert-butyl ester

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Paragraph 0037-0039; 0049-0053, (2021/07/09)

The invention provides a method for obta...

Method for producing long-chain diacid monoester

-

, (2018/08/03)

The invention provides a method for prod...

METHOD FOR THE SYNTHESIS OF DIACIDS OR DIESTERS FROM NATURAL FATTY ACIDS AND/OR ESTERS

-

Page/Page column 6, (2010/12/29)

The invention relates to a process for t...

INTRAMOLECULAR END-TO-END REACTIONS OF PHOTOACTIVE TERMINAL GROUPS LINKED BY POLYMETHYLENE CHAINS.

Ashikaga,Ito,Yamamoto,Nishijima

, p. 198 - 204 (2007/10/02)

Intramolecular end-to-end reactions of a...

2424-92-2 Process route

: tert-butyl icosanedioic acid

: 683239-16-9
eicosanedioic acid mono(1,1-dimethylethyl)ester

: 2424-92-2
octadecane-1,18-dicarboxylic acid

: 1767-98-2
20-methoxy-20-oxoicosanoic acid

Conditions

Conditions	Yield
With methanol; barium hydroxide octahydrate; at 30 - 35 ℃; for 14.5h;

: 50530-12-6
10-bromodecanoic acid

: 683239-16-9
eicosanedioic acid mono(1,1-dimethylethyl)ester

: 2424-92-2
octadecane-1,18-dicarboxylic acid

: 1767-98-2
20-methoxy-20-oxoicosanoic acid

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: trifluoroacetic anhydride / dichloromethane / 0.5 h / 0 °C / Large scale 1.2: 2 h / 0 - 10 °C / Large scale 2.1: zinc; nickel(II) chloride hexahydrate; 2,2':6,2''-terpyridine / N,N-dimethyl-formamide / 10 h / 35 - 45 °C / Inert atmosphere; Large scale 3.1: barium hydroxide octahydrate; methanol / 14.5 h / 30 - 35 °C With methanol; 2,2':6,2''-terpyridine; nickel(II) chloride hexahydrate; barium hydroxide octahydrate; trifluoroacetic anhydride; zinc; In dichloromethane; N,N-dimethyl-formamide;

Yield

Multi-step reaction with 3 steps

1.1: trifluoroacetic anhydride / dichloromethane / 0.5 h / 0 °C / Large scale

1.2: 2 h / 0 - 10 °C / Large scale

2.1: zinc; nickel(II) chloride hexahydrate; 2,2':6,2''-terpyridine / N,N-dimethyl-formamide / 10 h / 35 - 45 °C / Inert atmosphere; Large scale

3.1: barium hydroxide octahydrate; methanol / 14.5 h / 30 - 35 °C

With methanol; 2,2':6,2''-terpyridine; nickel(II) chloride hexahydrate; barium hydroxide octahydrate; trifluoroacetic anhydride; zinc; In dichloromethane; N,N-dimethyl-formamide;