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5006-66-6

  • Product Name2-Hydroxy-5-pyridinecarboxylic acid
  • Molecular FormulaC6H5NO3
  • Molecular Weight139.111
  • Purity99%
  • AppearanceOff-white powder
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Quick Details

  • CasNo： 5006-66-6
  • Molecular Formula： C6H5NO3
  • Appearance： Off-white powder
  • Purity： 99%

Trustworthy Factory Supply High Purity 2-Hydroxy-5-pyridinecarboxylic acid 5006-66-6 with the Best Price

  • Molecular Formula:C6H5NO3
  • Molecular Weight:139.111
  • Appearance/Colour:Off-white powder 
  • Vapor Pressure:5.81E-07mmHg at 25°C 
  • Melting Point:300 °C(lit.) 
  • Refractive Index:1.5423 (estimate) 
  • Boiling Point:384 °C at 760 mmHg 
  • PKA:3.80±0.50(Predicted) 
  • Flash Point:186 °C 
  • PSA：70.16000 
  • Density:1.451 g/cm3 
  • LogP:0.07310 

2-Hydroxy-5-pyridinecarboxylic acid(Cas 5006-66-6) Usage

Chemical Properties

Off-white powder

Uses

6-Hydroxynicotinic acid is used as building block in chemical synthesis.

Definition

ChEBI: A monohydroxypyridine that is the 6-hydroxy derivative of nicotinic acid.

General Description

6-Hydroxypyridine-3-carboxylic acid (6-Hydroxynicotinic acid) reacts with Ln(2)O(3) (Ln = Nd, Sm, Eu, Gd) and oxalic acid (H(2)OX) to generate four novel lanthanide-organic coordination polymeric networks.

Purification Methods

It crystallises from water with m 303.4-303.7o(dec), or with m 325o(dec) from aqueous EtOH. The methyl ester crystallises from Me2CO with m 166o and pK2 0 9.92. [Albert J Chem Soc 1020 1960, Beilstein 22 III/IV 2147, 22/6 V 119.]

InChI:InChI=1/C6H5NO3/c8-5-2-1-4(3-7-5)6(9)10/h1-3H,(H,7,8)(H,9,10)/p-1

5006-66-6 Relevant articles

Bioelectrochemically accelerated microbial conversion of nicotinic acid to 6-hydroxynicotinic acid on microorganism-immobilized column electrolytic flow system

Torimura, Masaki,Yoshida, Hideto,Kano, Kenji,Ikeda, Tokuji,Nagasawa, Toru,Ueda, Teruhisa

, p. 295 - 296 (1998)

Nicotinic acid (NA) is efficiently hydro...

Production of 6-hydroxynicotinic acid from nicotinic acid by resting cells of Pseudomonas fluorescens TN5

Nagasawa,Hurh,Yamane

, p. 665 - 668 (1994)

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A 6 - chloro nicotinic acid preparation method and separation and purification method

-

Paragraph 0035; 0039-0092, (2017/08/24)

The invention discloses a preparation me...

CYP199A4 catalyses the efficient demethylation and demethenylation of para-substituted benzoic acid derivatives

Coleman, Tom,Chao, Rebecca R.,Bruning, John B.,De Voss, James J.,Bell, Stephen G.

, p. 52007 - 52018 (2015/06/25)

The cytochrome P450 enzyme CYP199A4, fro...

Photochemistry of the three carboxypyridines in water: A pH dependent reaction

Rollet, Florence,Richard, Claire,Pilichowski, Jean-Francois,Aboab, Bettina

, p. 2253 - 2261 (2007/10/03)

The photochemistry of ortho, meta and pa...

5006-66-6 Process route

triethylamine
121-44-8

triethylamine

6-hydroxy-3-pyridinecarboxylic acid
5006-66-6

6-hydroxy-3-pyridinecarboxylic acid

Conditions
Conditions Yield
With potassium hydroxide; acetic anhydride; In tetrachloromethane;
79%
2H-pyran-2-one-5-carboxylic acid
500-05-0

2H-pyran-2-one-5-carboxylic acid

6-hydroxy-3-pyridinecarboxylic acid
5006-66-6

6-hydroxy-3-pyridinecarboxylic acid

Conditions
Conditions Yield
With sodium tungstate; ammonia; at 50 ℃; for 10h; Temperature;
 

5006-66-6 Upstream products

  • 142-08-5
    142-08-5

    2-Pyridone

  • 15719-64-9
    15719-64-9

    methylammonium carbonate

  • 403-45-2
    403-45-2

    6-fluoronicotinic acid

  • 6311-35-9
    6311-35-9

    6-bromonicotinic acid

5006-66-6 Downstream products

  • 66171-50-4
    66171-50-4

    methyl 6-hydroxynicotinate

  • 18617-50-0
    18617-50-0

    ethyl 6-hydroxypyridine-3-carboxylate

  • 3719-45-7
    3719-45-7

    1-methyl-6-oxo-1,6-dihydro-pyridine-3-carboxylic acid

  • 142-08-5
    142-08-5

    2-Pyridone

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