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541-59-3

  • Product NameMaleimide
  • Molecular FormulaC4H3NO2
  • Molecular Weight97.0733
  • Purity99%
  • Appearanceslight yellow crystalline powder
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Product Details

Quick Details

  • CasNo: 541-59-3
  • Molecular Formula: C4H3NO2
  • Appearance: slight yellow crystalline powder
  • Purity: 99%

Reputable Manufacturer Supply Buy High Grade Maleimide 541-59-3 with Efficient Delivery 

  • Molecular Formula:C4H3NO2
  • Molecular Weight:97.0733
  • Appearance/Colour:slight yellow crystalline powder 
  • Melting Point:91-93 °C(lit.) 
  • Refractive Index:1.4543 (estimate) 
  • Boiling Point:244.073 °C at 760 mmHg 
  • PKA:8.52±0.20(Predicted) 
  • Flash Point:136.574 °C 
  • PSA:46.17000 
  • Density:1.366 g/cm3 
  • LogP:-0.47220 

Maleimide(Cas 541-59-3) Usage

Chemical Properties

slight yellow crystalline powder

Uses

Rhodium-catalyzed conjugate arylation with arylboronic acids.1

Definition

ChEBI: A cyclic dicarboximide in which the two carboacyl groups on nitrogen together with the nitogen itself form a 1H-pyrrole-2,5-dione structure.

General Description

Maleimide (2,5-Pyrroledione) is a new nanoparticle surface functional group which favors easy conjugation with cell penetration peptides. The conjugation is enabled via click chemistry to preserve its biofunctions.

Hazard

A poison.

Safety Profile

Poison by intraperitoneal and intravenous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

Purify it by sublimation in a vacuum. The UV has max at 216 and 280nm in EtOH. [de Wolf & van de Straete Bull Soc Chim Belg 44 288 1935, UV: Rondestvedt et al. J Am Chem Soc 78 6115 1956, IR: Chiorboli & Mirone Ann Chim (Rome) 42 681 1952, Beilstein 21/10 V 3.]

Consumer Uses

ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

InChI:InChI=1/C4H3NO2/c6-3-1-2-4(7)5-3/h1-2H,(H,5,6,7)

541-59-3 Relevant articles

Preparation method of maleimide

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Paragraph 0061; 0066-0069; 0070; 0075-0078, (2022/03/27)

The invention provides a preparation met...

METHOD OF PRODUCING MALEIMIDE

-

Paragraph 0019, (2020/09/24)

PROBLEM TO BE SOLVED: To provide a metho...

Chemical-Switching Strategy for Synthesis and Controlled Release of Norcantharimides from a Biomass-Derived Chemical

Chang, Hochan,Huber, George W.,Dumesic, James A.

, p. 5213 - 5219 (2020/08/27)

Catalytic strategies were developed to s...

Cp?Co(III)-Catalyzed C-H Alkylation with Maleimides Using Weakly Coordinating Carbonyl Directing Groups

Mandal, Rajib,Emayavaramban, Balakumar,Sundararaju, Basker

supporting information, p. 2835 - 2838 (2018/05/29)

A novel protocol for ortho-C-H alkylatio...

541-59-3 Process route

L-glutamic acid
56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6

L-glutamic acid

maleiimide
541-59-3,25721-74-8

maleiimide

Succinimide
123-56-8,89963-74-6

Succinimide

pyrrole
109-97-7,30604-81-0

pyrrole

β-Propiolactone
57-57-8

β-Propiolactone

3-Methylpyridine
108-99-6

3-Methylpyridine

ethanol
64-17-5

ethanol

acetic acid
64-19-7,77671-22-8

acetic acid

acrylonitrile
107-13-1,25014-41-9

acrylonitrile

7-deazahypoxanthine
3680-71-5

7-deazahypoxanthine

acetonitrile
75-05-8,26809-02-9

acetonitrile

propiononitrile
107-12-0

propiononitrile

Conditions
Conditions Yield
With oxygen; at 400 ℃; for 5.55556E-05h; under 760.051 Torr; Temperature; Inert atmosphere; Pyrolysis; Gas phase; Flow reactor;
 
L-glutamic acid
56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6

L-glutamic acid

2-methyl-1H-pyrrole
636-41-9

2-methyl-1H-pyrrole

2-pyrrolidinon
616-45-5

2-pyrrolidinon

2-Pyridone
142-08-5,1199357-22-6

2-Pyridone

maleiimide
541-59-3,25721-74-8

maleiimide

Succinimide
123-56-8,89963-74-6

Succinimide

pyrrole
109-97-7,30604-81-0

pyrrole

7-deazahypoxanthine
3680-71-5

7-deazahypoxanthine

acetonitrile
75-05-8,26809-02-9

acetonitrile

Conditions
Conditions Yield
at 400 ℃; for 5.55556E-05h; under 760.051 Torr; Temperature; Inert atmosphere; Pyrolysis; Gas phase; Flow reactor;
 

541-59-3 Upstream products

  • 123-56-8
    123-56-8

    Succinimide

  • 109-97-7
    109-97-7

    pyrrole

  • 3345-50-4
    3345-50-4

    N-carbamoylmaleimide

  • 99362-76-2
    99362-76-2

    2,5-dioxo-2,5-dihydro-pyrrole-1-carboxylic acid tert-butylamide

541-59-3 Downstream products

  • 5677-70-3
    5677-70-3

    (+/-)-(3ar,6ac)-3a,6a-dihydro-3H-pyrrolo[3,4-c]pyrazole-4,6-dione

  • 6253-28-7
    6253-28-7

    exo-7-oxabicyclo[2.2.1]hept-4-ene-2,3-dicarboximide

  • 19878-26-3
    19878-26-3

    (3aR,4R,7S,7aS)-3a,4,7,7a-tetrahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione

  • 5615-81-6
    5615-81-6

    3-(phenylamino)pyrrolidine-2,5-dione

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