What is the 4-Cloromethyl-5-methyl-1,3-dioxol-2-one?

4-Cloromethyl-5-methyl-1,3-dioxol-2-one is Pale yellow transparent liquid, while it's Molecular Formula is C5H5ClO3. Pale yellow transparent liquid 4-Chloromethyl-5-methyl-1,3-dioxol-2-one is an important reagent in the preparation of angiotensin II receptor antagonist such as Olmesratan Medoxomil (O550000). 4-Chloromethyl-5-methyl-1,3-dioxol-2-one is also used in the preparation of prodrugs of ampicillin.

What is the CAS number for 4-Cloromethyl-5-methyl-1,3-dioxol-2-one?

The CAS number of 4-Cloromethyl-5-methyl-1,3-dioxol-2-one is 80841-78-7.

Trustworthy Manufacturer Supply Top Purity 99% 4-Cloromethyl-5-methyl-1,3-dioxol-2-one 80841-78-7 Customized Supply

Product Details

Quick Details

CasNo： 80841-78-7
Molecular Formula： C₅H₅ClO₃
Appearance： Pale yellow transparent liquid
Purity： 99%

Trustworthy Manufacturer Supply Top Purity 99% 4-Cloromethyl-5-methyl-1,3-dioxol-2-one 80841-78-7 Customized Supply

Molecular Formula:C5H5ClO3
Molecular Weight:148.546
Appearance/Colour:Pale yellow transparent liquid
Vapor Pressure:2.085mmHg at 25°C
Refractive Index:1.481
Boiling Point:163.228 °C at 760 mmHg
Flash Point:66.729 °C
PSA：43.35000
Density:1.362 g/cm³
LogP:1.28000

4-Cloromethyl-5-methyl-1,3-dioxol-2-one(Cas 80841-78-7) Usage

Chemical Properties	4-Cloromethyl-5-methyl-1,3-dioxol-2-one is Pale Yellow Oil
Uses	4-Chloromethyl-5-methyl-1,3-dioxol-2-one is an important reagent in the preparation of angiotensin II receptor antagonist such as Olmesratan Medoxomil (O550000). 4-Chloromethyl-5-methyl-1,3-dioxol-2-one is also used in the preparation of prodrugs of ampicillin.

InChI:InChI=1/C5H5ClO3/c1-3-4(2-6)9-5(7)8-3/h2H2,1H3

80841-78-7 Relevant articles

Preparation method of olmesartan medoxomil key intermediate

-

Paragraph 0017-0025, (2021/08/07)

The invention discloses a preparation me...

Method for catalytically synthesizing high-purity 4-chloromethyl-5-methyl-1,3-dioxol-2-one

-

Paragraph 0027-0038, (2020/07/06)

The invention belongs to the technical f...

A 4 - chloro methyl -5 - methyl - 1, 3 - dioxo heterocyclic pentene -2 - one purification method

-

Paragraph 0023-0050, (2019/03/21)

The invention discloses a purification m...

Preparation method for 4-chloromethyl-5-methyl-1,3-dioxol-2-one

-

Paragraph 0015-0022, (2018/04/21)

The invention specifically relates to a ...

80841-78-7 Process route

: 37830-90-3
4,5-Dimethyl-1,3-dioxole-2-one

: 80841-78-7
4-chloromethyl-5-methyl-1,3-dioxol-2-one

Conditions

Conditions	Yield
With chlorine; In 1,2-dichloro-ethane; for 0.5h; Solvent; Reagent/catalyst; Reflux; Molecular sieve;	89.3%
With N-chloro-succinimide; In tetrachloromethane; for 80h; Ambient temperature; Irradiation;	9.2%
With chlorine; copper; Yield given. Multistep reaction; 1.) dichloromethane, 90 min, reflux, 2.) dichloromethane, 2 h, reflux;
With sulfuryl dichloride; In dichloromethane;
With N-chloro-succinimide; dibenzoyl peroxide; at 90 ℃; for 5.5h; Temperature; Solvent; Large scale;	326 g
With 2,2'-azobis(isobutyronitrile); trichloroisocyanuric acid; In dichloromethane; for 3h; Reagent/catalyst; Irradiation; Reflux; Large scale;

: 95579-71-8
4-chloro-4-methyl-5-methylene-1,3-dioxolane-2-one

: 80841-78-7
4-chloromethyl-5-methyl-1,3-dioxol-2-one

Conditions

Conditions	Yield
at 75 - 80 ℃; for 4h;	87%

at 85 ℃; Temperature;	53.3 g

80841-78-7 Upstream products

37830-90-3
4,5-Dimethyl-1,3-dioxole-2-one
95579-71-8
4-chloro-4-methyl-5-methylene-1,3-dioxolane-2-one

80841-78-7 Downstream products

111738-35-3
4-(4-Fluorophenyl)thiomethyl-5-methyl-1,3-dioxol-2-one
111738-30-8
4-(4-Methoxyphenyl)thiomethyl-5-methyl-1,3-dioxol-2-one
111738-22-8
Sodium 4-((5-Methyl-2-oxo-1,3-dioxol-4-yl)methylthio)benzenesulfonate
111738-26-2
2-Chloro-5-((5-methyl-2-oxo-1,3-dioxol-4-yl)methylthio)benzoic Acid

;

Home

About us

Products

API

Amino acid

Biochemical Engineering

Organic Chemistry

Chemical Reagents

Pharmaceutical intermediates

Flavors and fragrances

Analytical Chemistry

Amino acid

Contact Us

80841-78-7

Quick Details

Trustworthy Manufacturer Supply Top Purity 99% 4-Cloromethyl-5-methyl-1,3-dioxol-2-one 80841-78-7 Customized Supply

4-Cloromethyl-5-methyl-1,3-dioxol-2-one(Cas 80841-78-7) Usage

80841-78-7 Relevant articles

Preparation method of olmesartan medoxomil key intermediate

-

Paragraph 0017-0025, (2021/08/07)

Method for catalytically synthesizing high-purity 4-chloromethyl-5-methyl-1,3-dioxol-2-one

-

Paragraph 0027-0038, (2020/07/06)

A 4 - chloro methyl -5 - methyl - 1, 3 - dioxo heterocyclic pentene -2 - one purification method

-

Paragraph 0023-0050, (2019/03/21)

Preparation method for 4-chloromethyl-5-methyl-1,3-dioxol-2-one

-

Paragraph 0015-0022, (2018/04/21)

80841-78-7 Process route

80841-78-7 Upstream products

80841-78-7 Downstream products

Relevant Products

Contact Now

Contact us

Maps

links