187393-00-6

  • Product NameBIS-ETHYLHEXYLOXYPHENOL METHOXYPHENYL TRIAZINE
  • Molecular FormulaC38H49N3O5
  • Molecular Weight627.824
  • Purity99%
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Product Details

Quick Details

  • CasNo: 187393-00-6
  • Molecular Formula: C38H49N3O5
  • Purity: 99%

Trustworthy Manufacturer Supply Buy Reliable Quality BIS-ETHYLHEXYLOXYPHENOL METHOXYPHENYL TRIAZINE 187393-00-6 with Safe Delivery 

  • Molecular Formula:C38H49N3O5
  • Molecular Weight:627.824
  • Vapor Pressure:1.37E-13mmHg at 25°C 
  • Melting Point:83-85°; mp 80° (Mongiat) 
  • Boiling Point:781.977 °C at 760 mmHg 
  • PKA:8.08±0.40(Predicted) 
  • Flash Point:426.724 °C 
  • PSA:106.82000 
  • Density:1.11 g/cm3 
  • LogP:9.48280 

BIS-ETHYLHEXYLOXYPHENOL METHOXYPHENYL TRIAZINE(Cas 187393-00-6) Usage

Description

Bemotrizinol, or bis-ethylhexyloxyphenol methoxyphenyl triazine, is an organic UV filter found in over-the-counter sunscreen products. It primarily absorbs UV-A rays. Compared to older broad-spectrum chemical agents, bemotrizinol is more more fat soluble (oil soluble in cosmetic oils) to aid in efficacy and broad-spectrum activity. It is claimed to be photostable, which increases its onset of action and its efficiency in providing protection against UV-rays upon topical application. Bemotrizinol is commonly marketed as Tinosorb S and Escalol S.

Uses

Bemotrizinol is a broad-spectrum UV absorber, absorbing both UVA and UVB. Bemotrizinol is added to various sunscreens to absorb UV rays.

Brand name

Tinosorb S (Ciba Specialty Chemicals).

Flammability and Explosibility

Nonflammable

Safety

Because bemotrizinol is relatively new to the sunscreen market there are few reports or studies available documenting its adverse effects and long term use. Studies to date have shown it to have a good safety profile. It is not significantly absorbed into the skin and rarely causes skin irritation. Unlike some other organic sunscreen agents, in vitro studies show that bemotrizinol does not appear to have hormonal effects. Further long-term human safety studies are required.

Regulations

Bemotrizinol is approved for use in Europe and Australasia. It is marketed under the brand names Tinosorb S and Escalol S. It is currently awaiting FDA approval so is not available in the USA.

InChI:InChI:1S/C38H49N3O5/c1-6-10-12-26(8-3)24-45-30-18-20-32(34(42)22-30)37-39-36(28-14-16-29(44-5)17-15-28)40-38(41-37)33-21-19-31(23-35(33)43)46-25-27(9-4)13-11-7-2/h14-23,26-27,42-43H,6-13,24-25H2,1-5H3

187393-00-6 Relevant articles

Preparation method of high-purity bis-ethyl hexyloxyphenol methoxyphenyl triazine

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Paragraph 0041-0069, (2021/09/26)

The invention particularly discloses a p...

Etherification synthesis method of ultraviolet light absorberTinosorb S

-

Paragraph 0032; 0037-0044; 0049-0051; 0056-0058; 0063; ..., (2021/07/24)

The invention discloses an etherificatio...

Manufacturing method of triazine-based compound and derivative thereof

-

, (2021/05/25)

The present invention relates to a triaz...

Manufacturing method of triazine-based compound and derivative thereof

-

, (2020/03/17)

The present invention relates to a triaz...

187393-00-6 Process route

2,4-dichloro-6-(4-methoxy-phenyl)-[1,3,5]triazine
90723-86-7

2,4-dichloro-6-(4-methoxy-phenyl)-[1,3,5]triazine

recorcinol
108-46-3

recorcinol

tinosorb S
187393-00-6

tinosorb S

4-[4-(2,4-dihydroxyphenyl)-6-(4-methoxyphenyl)-1,3,5-triazin-2-yl]benzene-1,3-diol
1440-00-2

4-[4-(2,4-dihydroxyphenyl)-6-(4-methoxyphenyl)-1,3,5-triazin-2-yl]benzene-1,3-diol

Conditions
Conditions Yield
aluminium chloride; In sulfolane; methanol; 5,5-dimethyl-1,3-cyclohexadiene;
 
2,4-dichloro-6-(4-methoxy-phenyl)-[1,3,5]triazine
90723-86-7

2,4-dichloro-6-(4-methoxy-phenyl)-[1,3,5]triazine

3-ethylhexyloxyphenol

3-ethylhexyloxyphenol

tinosorb S
187393-00-6

tinosorb S

Conditions
Conditions Yield
2,4-dichloro-6-(4-methoxy-phenyl)-[1,3,5]triazine; 3-ethylhexyloxyphenol; With aluminum (III) chloride; In chlorobenzene; at 40 - 60 ℃;
In water; at 40 - 60 ℃;
91.9%

187393-00-6 Upstream products

  • 90723-86-7
    90723-86-7

    2,4-dichloro-6-(4-methoxy-phenyl)-[1,3,5]triazine

  • 108-46-3
    108-46-3

    recorcinol

  • 123-04-6
    123-04-6

    3-(chloromethyl)heptane

  • 1440-00-2
    1440-00-2

    4-[4-(2,4-dihydroxyphenyl)-6-(4-methoxyphenyl)-1,3,5-triazin-2-yl]benzene-1,3-diol

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