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2215-77-2

  • Product Name4-PHENOXYBENZOIC ACID
  • Molecular FormulaC13H10O3
  • Molecular Weight214.221
  • Purity99%
  • Appearancewhite to slightly yellow crystalline powder
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Product Details

Quick Details

  • CasNo: 2215-77-2
  • Molecular Formula: C13H10O3
  • Appearance: white to slightly yellow crystalline powder
  • Purity: 99%

Reputable Manufacturer Supply Reliable Quality 4-PHENOXYBENZOIC ACID 2215-77-2 with Safe Shipping

  • Molecular Formula:C13H10O3
  • Molecular Weight:214.221
  • Appearance/Colour:white to slightly yellow crystalline powder 
  • Vapor Pressure:6.07E-06mmHg at 25°C 
  • Melting Point:163-165 °C(lit.) 
  • Refractive Index:1.5090 (estimate) 
  • Boiling Point:364.2 °C at 760 mmHg 
  • PKA:4.57(at 25℃) 
  • Flash Point:141.7 °C 
  • PSA:46.53000 
  • Density:1.241 g/cm3 
  • LogP:3.17710 

4-PHENOXYBENZOIC ACID(Cas 2215-77-2) Usage

Chemical Properties

white to slightly yellow crystalline powder

Uses

4-Phenoxybenzoic acid can block DNA binding of the human papillomarvirus (HPV) E2 protein. It is employed as an intermediate of Sitafloxacin, which is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer.

Definition

ChEBI: A phenoxybenzoic acid in which the phenoxy group is para to the carboxy group.

Safety Profile

A poison by intravenous route. When heated to decomposition it emits acrid smoke and irritating vapors.

InChI:InChI=1/C13H10O3/c14-13(15)10-6-8-12(9-7-10)16-11-4-2-1-3-5-11/h1-9H,(H,14,15)/p-1

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2215-77-2 Process route

4-Bromodiphenyl ether
101-55-3

4-Bromodiphenyl ether

carbon dioxide
124-38-9,18923-20-1

carbon dioxide

diphenylether
101-84-8

diphenylether

4-Phenoxybenzoic acid
2215-77-2

4-Phenoxybenzoic acid

Conditions
Conditions Yield
With 1,2-bis(diphenylphosphino)ethane nickel(II) chloride; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; for 10h; Ambient temperature; electrochemically;
1 mmol
86%
4-phenoxybenzoic acid ethyl ester
31994-68-0

4-phenoxybenzoic acid ethyl ester

4-Phenoxybenzoic acid
2215-77-2

4-Phenoxybenzoic acid

Conditions
Conditions Yield
With water; sodium hydroxide; In tetrahydrofuran; ethanol; Reflux;
89%
With water; sodium hydroxide; In ethanol; for 3h; Reflux;
87%
With sodium hydroxide; In ethanol; water; for 3h; Reflux;
75%
With water; sodium hydroxide; In ethanol; for 3h; Reflux;
 
With lithium hydroxide; In tetrahydrofuran; methanol; at 20 ℃; for 0.5h;
 
With water; sodium hydroxide; In ethanol; at 80 ℃; for 1h;
 
With water; sodium hydroxide; In ethanol; for 3h; Reflux;
 

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