Your Location:Home >Products >Fine chemicals >622-47-9

622-47-9

  • Product Name4-Methylphenylacetic acid
  • Molecular FormulaC9H10O2
  • Molecular Weight150.177
  • Purity99%
  • Appearancewhite fine crystalline powder
Inquiry

Product Details

Quick Details

  • CasNo: 622-47-9
  • Molecular Formula: C9H10O2
  • Appearance: white fine crystalline powder
  • Purity: 99%

Quality Manufacturer Supply Buy High Grade 4-Methylphenylacetic acid 622-47-9 with Low Price

  • Molecular Formula:C9H10O2
  • Molecular Weight:150.177
  • Appearance/Colour:white fine crystalline powder 
  • Vapor Pressure:0.00442mmHg at 25°C 
  • Melting Point:90-93 ºC 
  • Refractive Index:1.5002 (estimate) 
  • Boiling Point:265-267 ºC 
  • PKA:pK1:4.370 (25°C) 
  • Flash Point:173.5 ºC 
  • PSA:37.30000 
  • Density:1.127 g/cm3 
  • LogP:1.62210 

4-Methylphenylacetic acid(Cas 622-47-9) Usage

Chemical Properties

white fine crystalline powder

Uses

p-Tolylacetic acid is a reagent used in the preparation of quaternary amines and epithelial sodium channel inhibition in bronchial epithelium.

Synthesis Reference(s)

The Journal of Organic Chemistry, 48, p. 1919, 1983 DOI: 10.1021/jo00159a031Tetrahedron Letters, 28, p. 2633, 1987 DOI: 10.1016/S0040-4039(00)96167-7

Purification Methods

Crystallise the acid from heptane or water. [Beilstein 9 IV 1795.]

InChI:InChI=1/C9H10O2/c1-7-2-4-8(5-3-7)6-9(10)11/h2-5H,6H2,1H3,(H,10,11)/p-1

622-47-9 Relevant articles

A mild and efficient carboxylate-directed C-H arylation of aryl carboxylic acids with iodobenzenes in water

Xu, Zhongmiao,Yang, Ting,Lin, Xichen,Elliott, John D.,Ren, Feng

, p. 475 - 477 (2015)

An efficient and environmental friendly ...

Desulfonylative Electrocarboxylation with Carbon Dioxide

Zhong, Jun-Song,Yang, Zi-Xin,Ding, Cheng-Lin,Huang, Ya-Feng,Zhao, Yi,Yan, Hong,Ye, Ke-Yin

supporting information, p. 16162 - 16170 (2021/09/02)

Electrocarboxylation of organic halides ...

The thiol-based reduction of Bi(V) and Sb(V) anti-leishmanial complexes

Duffin, Rebekah N.,Stephens, Liam J.,Blair, Victoria L.,Kedzierski, Lukasz,Andrews, Philip C.

, (2021/05/10)

Low molecular weight thiols including tr...

Aerobic epoxidation of styrene over Zr-based metal-organic framework encapsulated transition metal substituted phosphomolybdic acid

Hu, Dianwen,Song, Xiaojing,Zhang, Hao,Chang, Xinyu,Zhao, Chen,Jia, Mingjun

, (2021/04/19)

Catalytic epoxidation of styrene with mo...

Visible-Light-Enabled Carboxylation of Benzyl Alcohol Derivatives with CO2 Using a Palladium/Iridium Dual Catalyst

Iwasawa, Nobuharu,Jin, Yushu,Toriumi, Naoyuki

, (2021/12/14)

A highly efficient carboxylation of benz...

622-47-9 Process route

diethyl ether
60-29-7,927820-24-4

diethyl ether

methylammonium carbonate
15719-64-9,15719-76-3,97762-63-5

methylammonium carbonate

4-methyl-benzyl magnesium <sup>(1+)</sup>; bromide

4-methyl-benzyl magnesium (1+); bromide

4-tolylacetic acid
622-47-9

4-tolylacetic acid

2,5-dimethylbenzoic acid
610-72-0

2,5-dimethylbenzoic acid

Conditions
Conditions Yield
 
 
N-Methyl-N-(4-nitro-phenyl)-2-p-tolyl-acetamide

N-Methyl-N-(4-nitro-phenyl)-2-p-tolyl-acetamide

4-tolylacetic acid
622-47-9

4-tolylacetic acid

N-methyl(p-nitroaniline)
100-15-2

N-methyl(p-nitroaniline)

Conditions
Conditions Yield
With barium dihydroxide; cetyltrimethylammonim bromide; In water; at 30 ℃; Rate constant; Mechanism; dependence of rate constant on concentration of cetyltrimethylammonium bromide;
 

622-47-9 Upstream products

  • 2947-61-7
    2947-61-7

    (4-methylphenyl)acetonitrile

  • 111-65-9
    111-65-9

    octane

  • 106-42-3
    106-42-3

    para-xylene

  • 1822-71-5
    1822-71-5

    n-pentylsodium

622-47-9 Downstream products

  • 37985-11-8
    37985-11-8

    (E,E)-1-(4-methylphenyl)-4-phenylbuta-1,3-diene

  • 27695-13-2
    27695-13-2

    3-(4-methylbenzyliden)-3H-isobenzofuran-1-one

  • 102456-03-1
    102456-03-1

    p-tolyl-acetic acid dodecyl ester

  • 102755-04-4
    102755-04-4

    3ξ-(trans-stilben-4-yl)-2-p-tolyl-acrylic acid

;

Relevant Products