What is the 4-Methylphenylacetic acid?

4-Methylphenylacetic acid is white fine crystalline powder, while it's Molecular Formula is C9H10O2. white fine crystalline powder p-Tolylacetic acid is a reagent used in the preparation of quaternary amines and epithelial sodium channel inhibition in bronchial epithelium.

What is the CAS number for 4-Methylphenylacetic acid?

The CAS number of 4-Methylphenylacetic acid is 622-47-9.

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Product Details

Quick Details

CasNo： 622-47-9
Molecular Formula： C₉H₁₀O₂
Appearance： white fine crystalline powder
Purity： 99%

Quality Manufacturer Supply Buy High Grade 4-Methylphenylacetic acid 622-47-9 with Low Price

Molecular Formula:C9H10O2
Molecular Weight:150.177
Appearance/Colour:white fine crystalline powder
Vapor Pressure:0.00442mmHg at 25°C
Melting Point:90-93 ºC
Refractive Index:1.5002 (estimate)
Boiling Point:265-267 ºC
PKA:pK1:4.370 (25°C)
Flash Point:173.5 ºC
PSA：37.30000
Density:1.127 g/cm³
LogP:1.62210

4-Methylphenylacetic acid(Cas 622-47-9) Usage

Chemical Properties	white fine crystalline powder
Uses	p-Tolylacetic acid is a reagent used in the preparation of quaternary amines and epithelial sodium channel inhibition in bronchial epithelium.
Synthesis Reference(s)	The Journal of Organic Chemistry, 48, p. 1919, 1983 DOI: 10.1021/jo00159a031Tetrahedron Letters, 28, p. 2633, 1987 DOI: 10.1016/S0040-4039(00)96167-7
Purification Methods	Crystallise the acid from heptane or water. [Beilstein 9 IV 1795.]

InChI:InChI=1/C9H10O2/c1-7-2-4-8(5-3-7)6-9(10)11/h2-5H,6H2,1H3,(H,10,11)/p-1

622-47-9 Relevant articles

A mild and efficient carboxylate-directed C-H arylation of aryl carboxylic acids with iodobenzenes in water

Xu, Zhongmiao,Yang, Ting,Lin, Xichen,Elliott, John D.,Ren, Feng

, p. 475 - 477 (2015)

An efficient and environmental friendly ...

Desulfonylative Electrocarboxylation with Carbon Dioxide

Zhong, Jun-Song,Yang, Zi-Xin,Ding, Cheng-Lin,Huang, Ya-Feng,Zhao, Yi,Yan, Hong,Ye, Ke-Yin

supporting information, p. 16162 - 16170 (2021/09/02)

Electrocarboxylation of organic halides ...

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Duffin, Rebekah N.,Stephens, Liam J.,Blair, Victoria L.,Kedzierski, Lukasz,Andrews, Philip C.

, (2021/05/10)

Low molecular weight thiols including tr...

Aerobic epoxidation of styrene over Zr-based metal-organic framework encapsulated transition metal substituted phosphomolybdic acid

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, (2021/04/19)

Catalytic epoxidation of styrene with mo...

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, (2021/12/14)

A highly efficient carboxylation of benz...

622-47-9 Process route

: 60-29-7,927820-24-4
diethyl ether

: 15719-64-9,15719-76-3,97762-63-5
methylammonium carbonate

: 4-methyl-benzyl magnesium ⁽¹⁺⁾; bromide

: 622-47-9
4-tolylacetic acid

: 610-72-0
2,5-dimethylbenzoic acid

Conditions

Conditions	Yield

: N-Methyl-N-(4-nitro-phenyl)-2-p-tolyl-acetamide

: 622-47-9
4-tolylacetic acid

: 100-15-2
N-methyl(p-nitroaniline)

Conditions

Conditions	Yield
With barium dihydroxide; cetyltrimethylammonim bromide; In water; at 30 ℃; Rate constant; Mechanism; dependence of rate constant on concentration of cetyltrimethylammonium bromide;

622-47-9 Upstream products

2947-61-7
(4-methylphenyl)acetonitrile
111-65-9
octane
106-42-3
para-xylene
1822-71-5
n-pentylsodium

622-47-9 Downstream products

37985-11-8
(E,E)-1-(4-methylphenyl)-4-phenylbuta-1,3-diene
27695-13-2
3-(4-methylbenzyliden)-3H-isobenzofuran-1-one
102456-03-1
p-tolyl-acetic acid dodecyl ester
102755-04-4
3ξ-(trans-stilben-4-yl)-2-p-tolyl-acrylic acid

;

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622-47-9

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Quality Manufacturer Supply Buy High Grade 4-Methylphenylacetic acid 622-47-9 with Low Price

4-Methylphenylacetic acid(Cas 622-47-9) Usage

622-47-9 Relevant articles

A mild and efficient carboxylate-directed C-H arylation of aryl carboxylic acids with iodobenzenes in water

Xu, Zhongmiao,Yang, Ting,Lin, Xichen,Elliott, John D.,Ren, Feng

, p. 475 - 477 (2015)

Desulfonylative Electrocarboxylation with Carbon Dioxide

Zhong, Jun-Song,Yang, Zi-Xin,Ding, Cheng-Lin,Huang, Ya-Feng,Zhao, Yi,Yan, Hong,Ye, Ke-Yin

supporting information, p. 16162 - 16170 (2021/09/02)

The thiol-based reduction of Bi(V) and Sb(V) anti-leishmanial complexes

Duffin, Rebekah N.,Stephens, Liam J.,Blair, Victoria L.,Kedzierski, Lukasz,Andrews, Philip C.

, (2021/05/10)

Aerobic epoxidation of styrene over Zr-based metal-organic framework encapsulated transition metal substituted phosphomolybdic acid

Hu, Dianwen,Song, Xiaojing,Zhang, Hao,Chang, Xinyu,Zhao, Chen,Jia, Mingjun

, (2021/04/19)

Visible-Light-Enabled Carboxylation of Benzyl Alcohol Derivatives with CO2 Using a Palladium/Iridium Dual Catalyst

Iwasawa, Nobuharu,Jin, Yushu,Toriumi, Naoyuki

, (2021/12/14)

622-47-9 Process route

622-47-9 Upstream products

622-47-9 Downstream products

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